In metastasis, cancer cells break away from the primary cancer, travel through the blood or lymph system, and form new, metastatic tumors in other parts of the body. Novocure is developing TTFields for different cancer diseases, such as: pancreatic cancer, ovarian cancer, lung cancer, mesothelioma and brain metastasis. Novocure is developing TTFields for different cancer diseases, such as: pancreatic cancer, ovarian cancer, lung cancer, mesothelioma and brain metastasis. Phase III study of TTFields combined with chemotherapy for newly-diagnosed pancreatic cancer  more... A phase III study of TTFields following Stereotactic Radiosurgery for 1-10 Brain Metastases from Non-Small-Cell Lung Cancer  more... TTFields have been approved by FDA for the treatment of adult patients suffering from newly diagnosed and recurrent glioblastoma. We believe we have gained a deep understanding of the underlying mechanism of action and the multiple pathways through which Tumor Treating Fields exert their effects within dividing cancer cells. Novocure ($7 billion, -20% YTD) is an oncology company that offers a novel therapy called Tumor Treating Fields, which uses electric fields to … The China expansion is in the initial stages and NovoCure expects to see royalty revenues in the upcoming quarters, as it has already received regulatory approval in Q2. Work on increasing awareness of Novocure clinical trials by coordinating campaigns in medical journals, and other non-personal media. We expect our colleagues to excel, and in return, we invest in their professional growth and … Meet our leaders, who have extensive experience across oncology, biotechnology and medical device industries. Our research shows that Tumor Treating Fields can have an anti-mitotic effect in 18 different solid tumor types in culture and in eight in vivo tumor models, including some of the most aggressive forms of cancer. clinical trials Our mechanism of action is broadly applicable across a variety of solid tumors. Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, non-small cell … … During her seventeen years with Novocure, she and the preclinical team have researched the effects of TTFields on a variety of solid tumor cancer cell lines and laid the foundation for Novocure’s expansion into additional clinical trials. TTFields is experimental for all indications mentioned in those clinical trials and has not been approved for their treatment. “There are few possibilities to treat these patients,” … The TRIDENT trial (also known as the “EF-32 trial”) is a randomized, controlled study, testing the safety and efficacy of Tumor Treating Fields (TTFields) from the Optune ® System [About TTFields] together … We have revised our Privacy Policy that is in effect as of May 25, 2018. Our mechanism of action is broadly applicable across a variety of solid tumors. Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, non-small cell lung cancer, pancreatic cancer, … The device is an experimental, portable, battery operated device for chronic administration of … Salaries posted anonymously by Novocure employees. Novocure Vulnerability Disclosure Process. Tumor Treating Fields (TTFields) are low intensity alternating electric fields tuned to disrupt the division process of cancer cells. Novocure is the sponsor of clinical trials testing TTFields in several cancers. Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, non-small cell lung cancer, pancreatic cancer, … Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, non-small cell lung cancer, pancreatic cancer, ovarian cancer, liver cancer and glioblastoma. clinical trials Novocure continues to test Tumor Treating Fields against a broad range of solid tumor types. The Clinical Trial Communications Associate will focus on writing and editing communications materials for our clinical trial efforts, including the website, patient/site-facing materials, and indirect channels in order to increase awareness of the … A phase III study of TTFields combined with chemotherapy for advanced Non-Small-Cell Lung Cancer. Brain metastases occur in roughly 15% of all cancer patients, and we believe that approximately 40% of brain metastases are a result of NSCLC. Here at Novocure, cancer patients and their families are – and have always been – at the core of our mission. novocuretrial.com The science of Tumor Treating Fields extends beyond glioblastoma. A free inside look at Novocure salary trends based on 24 salaries wages for 20 jobs at Novocure. Novocure's program centered on an 80-person clinical trial, the data from which persuaded FDA to approve the device under its rare disease pathway, HDE. Tumor Treating Fields (TTFields) are low intensity alternating electric fields tuned to disrupt the division process of cancer cells. NovoCure announced today that it has entered a clinical trial collaboration agreement with Merck.Together, the companies will develop Tumor Treating Fields with Merck’s anti-PD-1 therapy, Keytruda for the treatment of non-small cell lung cancer (NSCLC). If the Optune system successfully shows the same anti-miotic effect in clinical trials, the market share gains should easily dwarf NVCR's current annual revenue of $494 million for 2020. Tumor Treating Fields (TTFields) are low intensity alternating electric fields tuned to disrupt the division process of cancer cells. About brain metastases: Metastatic cancer is cancer that has spread from the place where it first started to another place in the body. Pancreatic cancer is the only major cancer with a five-year relative survival rate in the single digits, at just 8 percent. Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, non-small cell lung cancer, pancreatic cancer, ovarian cancer, liver cancer and … the incidence of ovarian cancer is approximately 22,500 new cases annually in the u.S., approximately 68,000 new cases annually in Europe, and approximately 10,000 new cases Approximately 214,000 new cases of NSCLC are diagnosed in the U.S. each year, approximately 350,000 new cases are diagnosed annually in Europe, and approximately 95,000 new cases are diagnosed annually in Japan. Tumor Treating Fields is experimental for the treatment of patients with brain metastases, ovarian carcinoma, pancreatic adenocarcinoma, mesothelioma and non-small cell lung cancer. Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in mesothelioma, brain metastases, non-small cell lung cancer, pancreatic cancer, ovarian cancer and liver cancer. Of the 214,000 Americans diagnosed with lung cancer annually, only 18% are alive five years later. This website intends to use cookies to improve the site and your experience. Headquartered in Jersey, Novocure has U.S. operations in Portsmouth, New Hampshire, Malvern, Pennsylvania and New York City. By continuing to browse the site you are agreeing to accept our use of cookies. … TTFields. On this site, videos and images identified as Optune users, caregivers or healthcare professionals depict actual patients, caregivers and healthcare professionals. Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, non-small cell lung cancer, pancreatic cancer, ovarian cancer, liver cancer and … Cancer type: Non-small cell lung cancer (Phase 3 pivotal). Advancing our clinical pipeline in indications with significant unmet need. The incidence of pancreatic cancer is 54,000 new cases annually in the United States, approximately 130,000 new cases annually in Europe, and approximately 39,000 new cases annually in Japan. Description: The Clinical Trial Associate supports the Clinical Trial Manager and Study Team with all operational and trial related activities from study start-up to close out.. The study is a prospective, randomized controlled phase III trial, to test the efficacy, safety and neurocognitive outcomes of advanced NSCLC patients, following stereotactic radiosurgery (SRS) for 1 … Interventional (Clinical Trial) Estimated Enrollment : 30 participants: Allocation: Non-Randomized: Intervention Model: Parallel Assignment: Intervention Model Description: Device: NovoCure … Additional investigator-sponsored trials are also ongoing. Salaries posted anonymously by Novocure employees. Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, non-small cell lung cancer, pancreatic cancer, ovarian cancer and liver cancer. annually in Japan. The exact incidence of brain metastases is unknown, but it has been estimated that 98,000 to 170,000 new cases are diagnosed in the United States each year. A large clinical study in recurrent GBM showed that Optune was as effective as chemotherapy, in certain quality of life measures, with people self-reporting*: Better quality of life. Hepatocellular carcinoma is the most widespread type of cancer that originates from the liver. The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of TTFields, using the NovoTTF-100L System, concurrent with standard therapies for stage 4 NSCLC patients, following progression while on or after platinum based treatment.The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields … We sponsor clinical trials of Tumor Treating Fields in several cancer types. About NSCLC: Lung cancer is the most common cause of cancer-related death worldwide, and non-small cell lung cancer accounts for approximately 85% of all lung cancers. Seattle Clinical Trial Associate, ROW - WA, 98119. We are committed to advancing the science of Tumor Treating Fields across a broad spectrum of solid tumors and bringing our treatment to cancer patients who can benefit from our therapy. In China, the company has partnered with biopharmaceutical firm Zai Lab (NASDAQ: ZLAB) to streamline distribution and accelerate clinical trial enrollment. TTFields are delivered to the region of the tumor using a portable medical device for continuous, home use. We sponsor clinical trials of Tumor Treating Fields in several cancer types. A large clinical study in recurrent GBM showed that Optune was as effective as chemotherapy, in certain quality of life measures, with people self-reporting*: Better quality of life. Dr. Kirson has global responsibility for Novocure’s preclinical and clinical and product development programs, as well as the company’s regulatory strategy. The five-year survival rate with existing standards of care is less than 18%. The Clinical Trial Communications Associate is responsible for supporting the Clinical Operations department in advancement of the company’s clinical program. For more information on our ongoing clinical trials, visit novocuretrial.com and clinicaltrials.gov. The science of Tumor Treating Fields extends beyond glioblastoma. We pioneer a profoundly different approach to treating cancer called Tumor Treating Fields. TTFields are delivered to the region of the tumor using a portable medical device for continuous, home use. Broad applicability of the mechanism of action. Eilon Kirson, Novocure’s former Chief Science Officer and Head of Research and Development, visited Dr. Vymazal in 2004 at Na Homolce Hospital in Prague, where Dr. Vymazal worked as a clinical neurologist and radiologist, to discuss running a clinical trial … Limited by federal law to investigational use only. … This information is for medical, and scientific and educational purposes only. “There … Novocure is developing TTFields for different cancer diseases. Novocure has ongoing or completed clinical trials and is further expanding its efforts into several other solid tumor indications - non-small cell lung cancer, pancreatic cancer, ovarian cancer and other types … Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, non-small cell lung cancer, pancreatic cancer, ovarian cancer and liver cancer. About pancreatic cancer: Pancreatic cancer is one of the most lethal cancers and is the third most frequent cause of death from cancer in the United States. The China expansion is in the initial stages and NovoCure … The study posted an overall survival of 18.2 months in people who received NovoTTF … Top of Page Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information. Novocure is the sponsor of clinical trials testing TTFields in several cancers. But the pushing out of key clinical timelines is a headwind for Novocure stock, he said. Novocure’s commercialized products are approved for the treatment of adult patients with glioblastoma and malignant pleural mesothelioma. About ovarian cancer: In the U.S., ovarian cancer ranks fifth in cancer deaths among women, accounting for more deaths than any other cancer of the female reproductive system. Preclinical and clinical data continue to suggest broad applicability of the mechanism of action behind TTFields, and … In China, the company has partnered with biopharmaceutical firm Zai Lab (NASDAQ: ZLAB) to streamline distribution and accelerate clinical trial enrollment. For the most up-to-date clinical trial information, including protocol details, please visit the U.S. National Institutes of Health’s website at clinicaltrials.gov. Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, non-small cell lung cancer, pancreatic cancer, ovarian cancer, liver cancer and gastric cancer. We seek high performers who thrive in fast-paced environments and are inspired by making a difference in cancer care. TTFields is currently being tested for other cancers in various clinical trials, presented in this website. Professor Yoram Palti founded Novocure in 2000. Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in brain metastases, non-small cell lung cancer, pancreatic cancer, ovarian cancer, liver cancer and … Novocure has ongoing or completed clinical trials investigating Tumor Treating Fields in mesothelioma, brain metastases, non-small cell lung cancer, pancreatic cancer, ovarian cancer and … He conducts 20 clinical trials in ovarian cancer per year and was an investigator in Novocure’s phase 2 pilot study in recurrent ovarian cancer, INNOVATE. The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFields) in combination with gemcitabine and nab-paclitaxel, for … Roza Shnayderman, Head of Novocure’s Israel Biology Lab, joined Novocure in March 2000. Novocure continues to test Tumor Treating Fields against a broad range of solid tumor types. Novocure maintains this website in order to assist patients, their family members and caregivers in accessing clinical trial sites for potential participation in ongoing trials. He conducts 20 clinical trials in ovarian cancer per year and was an investigator in Novocure’s phase 2 pilot study in recurrent ovarian cancer, INNOVATE. Novocure’s Chief Science Officer and Head of Research and Development Eilon Kirson, MD, PhD was one of the first employees to join the company in 2002. About hepatocellular cancer: Liver cancer is a leading cause of cancer deaths worldwide and is the seventh leading cause of cancer deaths annually in the U.S. novocuretrial.com The science of Tumor Treating Fields extends beyond glioblastoma. The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFields) concomitant with weekly paclitaxel for the treatment of recurrent ovarian cancer. 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